Tag Archives: Paul G. Allen

GETTING RID OF RESEARCH GRANTS: HOW PAUL G. ALLEN IS DOING IT! 

 

Quotations about scientific research from PAUL G. ALLEN! (http://dr-monsrs.net)
Quotations about scientific research from PAUL G. ALLEN, who knows what needs to be changed! (http://dr-monsrs.net)

 

The co-founder of Microsoft (1975), Paul G. Allen, has just made a large donation to start a dramatic new research program in biomedical science, the Paul G. Allen Frontiers Group.  My recent dispatch about this dynamic man briefly summarized his life interests, global activities, and accomplishments with supporting science and research (see: “A Dramatic Individualist, Paul G. Allen, is a Major Benefactor of Scientific Research!”).  The present article presents how Allen’s newest philanthropy for science is organized, explains what he is aiming for, and applauds his insight into what is wrong in science at modern universities.

The Paul G. Allen Frontiers Group [1-3]! 

The new Paul G. Allen Frontiers Group has 2 mechanisms for sponsoring research.  The Allen Discovery Centers provide $30 million to support productive research groups where ground-breaking investigations going into the future of science are underway.  The first 2 awards will go to Tufts University (Boston) for fundamental investigations on the genesis of organ and tissue structures, and to Stanford University (Palo Alto) for systems-level computational modeling of immune cell interactions with bacteria.  This portion of the Frontiers Group will fund up to 10 Discovery Centers.

The new Allen Distinguished Investigators are professional scientists working at various institutions around the world, and  can be either junior or senior researchers showing the potential to dramatically reinvent entire areas of science.  The awards of 1-1.5 million dollars for up to 25 selected scientists enable each to initiate unrestricted new directions for research in their respective fields.  The Distinguished Investigators receive 10 years of support, thereby encouraging studies of very large previously unapproachable research questions.  The freedom provided allows the Distinguished Investigators to study unusual subjects and use unconventional approaches.  These possibilities are particularly needed for breakthrough studies into the complexities of biomedical science.  Initial selection of 4 research scientists has just been announced; for details about their investigations, see “Video: Launch press conference: The Paul G. Allen Frontiers Group” .

What will be the influence of the Allen Frontiers Group on science [1-3]? 

The Allen Frontiers Group is revolutionary because it has several very distinctive features.  (1) The new awardees all are located outside the several large research institutes founded by Paul Allen in Seattle; thus, the influence of his philosophy for high quality science now will spread more widely.  (2) Awards in the Allen Frontiers Group all supersede the traditional approaches used to support science with research grants; the awardees can jump over the usual step-by-step progress made by individual scientists via using new and unconventional ideas for research that are too risky to be funded by research grants.  (3) The large amount of time university faculty scientists now need to waste dealing with research grants (see “What is the New Main Job of Faculty Scientists Today?” ) will become available for actual experimental work in their laboratory; federal grants will not be needed by the Distinguished Investigators.  (4) The awardees have a very unusual amount of unrestricted freedom for creativity and innovation; this encourages making advances in knowledge for topics and questions that are complex, difficult, and important.

The changed atmosphere provided by these factors should act to return university scientists toward finding important new knowledge through basic research, instead of chasing money from research grants.  Thus, research by investigators in the Allen Frontiers Group will have a large impact by greatly advancing their fields in bioscience.  Paul Allen is liberating faculty scientists to do better science, to investigate very difficult research questions, and, to once again have fun with their work (see: “Why are University Scientists Increasingly Upset with Their Job?  Part II” )!

Paul Allen must perceive exactly what is wrong with today’s university research! 

The classical belief that research scientists should be creative, inventive, fearless, and unhindered is increasingly not evident in modern universities.  The current research grant system is destructive and hinders bringing new ideas into basic research.  Freedom is missing to take chances on making research breakthroughs by using unconventional experiments.   Novel ideas must be repressed due to worries about not getting a grant renewed.  These widespread restrictions unfortunately limit research progress for all faculty scientists at universities, medical schools, and research institutes.  The improved working atmosphere in Allen’s design for research includes the freedom to think new thoughts and go against the flow, collaborate with teamwork instead of unbridled competition, and, develop unforeseen new concepts .

Other philanthropists also act to free faculty scientists from bad problems with the research grant system! 

I recently highlighted another remarkable philanthropic effort to rescue science from its present malaise by James E. Stowers, who established and generously endowed the Stowers Institute for Medical Research (see: “A Jackpot for Scientific Research, Part II” ).  His large new research institute has some similar features to the Allen Institutes, including that most financial  support is provided internally.  At least 2 different billionaires thus perceive the important advantages for science of using philanthropy to substitute for the perverse research grant system (see:  “Research Grants Cause Both Joy and Despair for University Scientists!” ).   In fact, several other megaphilanthropists recently have initiated support programs which strikingly advance university science [e.g., 1].

Concluding remarks! 

Paul Allen clearly recognizes the negative effects the current research grant system has upon scientific research in universities.  A key feature for investigators in the new Allen Frontiers Group is their liberation from the restrictions and distortions imposed by grant-supported research; they now have the freedom to make important research advances using creativity, innovation, and initiative while daring to take chances!

After reading my previous reports about the Stowers Medical Research Institute, many concluded that sponsorship of high quality scientific research by private philanthropy is NOT realistic because nobody else would donate the large sums of money needed.  Several other big donors show that they all are very wrong!  

It is easy to predict that the outcome of the new Frontiers Group generously sponsored by Paul G. Allen will be nothing short of wonderful!  He should be praised by all research scientists for recharging and improving scientific research at universities!  He truly is a hero in sience!  Hooray for Paul Allen!

 

[1]  Allen Institute, 2016.  “Press Release: Paul G. Allen Announces $100 million to Launch The Paul G. Allen Frontiers Group” .  Available on the internet at:  https://www.alleninstitute.org/what-we-do/frontiers-group/news-press/press-resources/press-releases/paul-g-allen-announces-100-million-launch-paul-g-allen-frontiers-group .

[2]  Cha, A. E., 2016.  Philanthropist Paul Allen announces $100 million gift to expand ‘frontiers of bioscience’.  The Washington Post, March 24, Section A, page A2.  Available on the internet at:  http://pqasb.pqarchiver.com/washingtonpost/doc/1775298386.html?FMT=FT&FMTS=ABS:FT&date=Mar+24%2C+2016&author=Ariana+Eunjung+Cha&desc=%24100+million+to+fund+exploration+of+biosciences&free=1&pf=1 .

[3]  The Paul G. Allen Frontiers Group, 2016.  “Video: Introducing The Paul G. Allen Frontiers Group” is available on the internet at:   https://www.youtube.com/watch?v=1bkLKuJigpY .

 

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A DRAMATIC INDIVIDUALIST, PAUL G. ALLEN, IS A MAJOR BENEFACTOR OF SCIENTIFIC RESEARCH! 

 

Quotations from Paul G. Allen, a most dynamic and revolutionary thinker and doer! (http://dr-monsrs.net)
Quotations from Paul G. Allen, a most dynamic and revolutionary thinker and doer! (http://dr-monsrs.net)

 

The co-founder of Microsoft (1975) , Paul G. Allen, has already given over 2 billion dollars to establish several far-sighted new research institutes.  He is a free-thinking man with numerous activities and widespread interests, ranging from music to professional sports and spaceflight.  This dispatch briefly summarizes the remarkable scope of Allen’s dynamic activities, and then discusses how his philanthropy is benefiting scientific research in a big way; a following article will discuss the very novel features of his latest innovative program for stimulating the progress of scientific research.  (POSTSCRIPT on June 5, 2016: readers should note that there is a followup posting about Paul Allen (see: http://dr-monsrs.net/2016/04/14/replacing-research-grants-how-paul-g-allen-is-doing-it/ )!

Background about a vigorously independent individual: Paul G. Allen [1-3]! 

Paul Allen is an author, business owner and investor, entrepreneur and industrialist, explorer of history and geography, founder of several museums, inventor, moviemaker, owner of several professional sports teams, promoter of urban projects in Seattle (his hometown!), rock guitarist, supporter of education and the arts, technological visionary, yachtsman, and, one of the world’s leading philanthropists.  In addition to working with his sister, Jody Allen, on many of those activities, he has utilized his Allen Family Foundation to greatly benefit several universities in the state of Washington, start the Allen Distinguished Educators program that rewards particularly creative and effective education developments by teachers in primary and secondary schools, support a non-governmental organization, Elephants Without Borders, to further the conservation of wild elephants in Africa, establish the Paul G. Allen Ocean Challenge as a public contest for improving the health of our oceans, along with stimulating a variety of other programs, projects, and personal explorations.  Most of this is carried out by his company, Vulcan, Inc.; one of its many activities is Vulcan Aerospace, a division  including a collaborative space exploration project with the noted engineer, Burt Rutan (see: “Stratolaunch Systems, A Paul G. Allen Project” ).

Tying all these many explorations together is Paul Allen’s extensive curiosity, diverse personal interests, determination to make ideas flow into new knowledge, affection for going where no-one has tread before, and, his optimistic belief that anything is possible.  For him, the future can be opened right now!  In 2005, Paul Allen published an autobiographical book, Idea Man, A Memoir by the Cofounder of Microsoft, recounting his experiences in co-originating Microsoft; 10 short videos based on this book graphically illustrate his youth and development of operating systems in the early days of personal computing (see “Idea Man Part One: Roots” ).

Paul G. Allen has advanced scientific research in revolutionary ways [1-3]! 

For trying to push science and research beyond all their usual goals and practices, Paul Allen founded and funded the Allen Institute for Brain Research in 2003, the Allen Institute for Artificial Intelligence in 2013, and, the Allen Institute for Cell Science in 2014.  These research centers in Seattle feature technologically advanced experimental research by scientists and engineers, and involve such very large and complex research questions as how does the brain work (i.e., how do some 86 billion neurons interact to furnish memory and reasoning?), what can artificial intelligence do for humans (i.e., as individuals and as society?), and how do our cells conduct their varied functions (i.e., in health, disease, and regeneration?).  These giant research investigations at these Institutes all are in the realm of “big science”.

The goals of Paul Allen are nothing less than to revolutionize science and speed up the progress of research.  To do that, he brought the practices of industrial research to bear at the Allen Institutes; these feature numerous doctoral specialists working as teams supported by a large staff and advanced research instrumentation facilities.  At the Institutes, there is little of the problems characterizing science at universities (i.e., massive individual competition, constant worries about continued research grant funding, and, doing niche studies needing only shorter periods of time).  Jumps of discovery are encouraged by creativity, innovation, and interactive teamwork.  Output of these large-scale science projects is made available as internet resources for use by other researchers throughout the world; examples include several Allen Atlases for the mouse and human brains in adulthood and during embryonic growth, the Allen Brain Cell Types Database, the Mouse Neural Connectivity Atlas, and The Animated Cell, a multiscale virtual model that integrates all knowledge about cells and can predict changes in their behavior.

The vision, organization, and goals of these research institutes mostly come from Paul himself.  He sees that science and technology can make dreams become real; he values unconventional new ideas that stimulate groundbreaking findings and jump into the future.  All this aims to benefit the entire world and all people.

Concluding remarks! 

Paul G. Allen is a most dynamic individual!  He deserves admiration for using his own money to benefit science and engineering, the arts, Seattle, Africa, oceans, wildlife, museums, and people everywhere.  He clearly is making a big difference in the conduct of scientific research, by promoting a new design for research on very fundamental large-scale questions.  It is easy to predict that the outcome of his vision of what science and research should be doing will be nothing short of wonderful!

VIDEOS:  Many videos about Paul G. Allen both inside and outside science are available on the internet!  For a glimpse of the man himself, I recommend the following 3!

(1)  “Paul Allen on Gates, Microsoft” by CBS (2011); this presentation involves a hostile interviewer!

(2)  “Stratolaunch Systems: A Paul G. Allen Project” by Vulcan, Inc. (2011); turning ideas into reality!

(3)  “Paul G. Allen on Art” by Vulcan, Inc.  (2015); presents Allen’s many activities to make good art available to the public!

 

[1]  @PaulGAllen, 2016.  “Home page” .  Available on the internet at:  http://www.paulallen.com/ .  NOTE: explore the different headings!

[2]  Allen Institute for Brain Science, 2013.  “Allen Institute for Brain Science: Fueling Discovery” .  Available on the internet at:  https://www.youtube.com/watch?v=9HclD7T9KFg .

[3]  Allen Institutes, 2016.  “About” .  Available on the internet at:  http://www.alleninstitute.org/about/ . NOTE: explore the variety of headings indicating the diversity of Paul Allen’s many activities!

 

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